Tuesday, 3rd November ESA-SRB-NZSE-CaSR 2026 in conjunction with ENSA

Title: From Evidence to Evolution: Semaglutide in Obesity Care
Speaker: Professor Sarah Glastras

Join this interactive session discussing current and emerging evidence for semaglutide in obesity care. The session will cover weight management, cardiometabolic health and long-term disease risk, alongside emerging formulations and treatment approaches.

Pre-registration required.

This session is designed to foster the professional and personal development of SRB and NZSE early- and mid-career researchers. Small groups will connect with experienced mentors for informal discussion around career pathways, leadership, professional development and navigating a research career. The opportunity is open to postdoctoral fellows and independent researchers within 10 years of completing their PhD.

For ESA members only 

• Mechanisms of physiological activation and modulation of the calcium-sensing receptor: molecular origins of promiscuous G protein signaling - Qing R Fan
• Mechanisms of CaSR modulation and opportunities for drug discovery - Georgios Skiniotis
• From Conformational Sensing to Nanobody-Based Therapeutics for the CaSR - Jianfeng Liu

Followed by 9:30AM - Panel Discussion (Qing Fan, Yiorgo Skiniotis, Jianfeng Liu and Arthur Conigrave)

• The Genetic Origins of Aneuploid Eggs: New Insights into Reproductive Health - Karen Schindler

• What’s in an Age? Rethinking Diagnosis and Management in hyperinsulinism - Diva De Leon-Crutchlow

• From fat mice to zero gravity: a decade inside what sperm actually do during embryogenesis and how it built my career - Nicole McPherson

Award sponsored by: 

SRF Postdoc Exchange Winner - Dr Haoyang Ying

• Where, When and How? Towards understanding spatiotemporal control of FSHR signalling - Haoyang Ying

• The psychological and financial burden of lifelong surveillance in SDHB pathogenic variant carriers - Dahlia Davidoff
• Longitudinal aldosterone and renin trajectories and cardiovascular risk in young adults from the Raine Study - Sho Katsuragawa
• Targeted alerts to primary care physicians improve osteoporosis treatment after minimal trauma fracture: Outcomes of the INTERCEPT cluster-randomised controlled trial - Mawson Wang
• Pituitary tumour classification and risk stratification: predicting clinical outcomes in acromegaly - Prishila Fookeerah

• Understanding the control of CaSR signalling mechanisms by mutational analysis of receptor signalling and trafficking pathways - Caroline Gorvin
• Role of C-terminal phosphorylation in CaSR function - Donald Ward
• Biased CaSR Autoantibodies Reveal New Dimensions of Receptor Signaling and Autoimmunity - Noriko Makita
• Discovery and pharmacological characterization of nanobodies acting as potent positive allosteric modulators of the calcium-sensing receptor - Jesper Mathiesen

• Journey towards precision medicine in Diabetes and Obesity - Rinki Murphy
• Lipids Across the Lifespan: from 5-year risk to lifetime exposure - Huan Chan
• PMOS: Integrating metabolism, androgens and reproduction - Maritza Farrant

• Elevated decidual vascular remodelling and placental efficiency is elicited by maternal-fetal MHC disparity and mediated by maternal T cells - Uyen Pham
• Secretoglobins SCGB1D2 and SCGB2A1 as functional regulators of endometrial receptivity - Mojtaba Moradi
• LRPAP1 deficiency disrupts placental function in humans and mice - Yimiao Yu
• Chemotherapy exposure before pregnancy causes persistent placental defects and impaired postnatal growth - Jordan Higgins
• Establishing the first spermatogonial enrichment and biobanking pipeline for the koala (Phascolarctos cinereus) - Katerina B Damyanova
• Metformin treatment for diabetes in pregnancy increases placental size, decreases mitochondrial respiration and alters growth signalling and steroidogenesis of mouse placenta - Dayna A Zimmerman

Award sponsored by: 

• Single cell transcriptomic analysis of BRAF papillary thyroid cancer with and without lymphocytic thyroiditis - Sumathy Perampalam
• Native corticosteroid-binding globulin to treat life-threatening sepsis and septic shock. - Declan E Kilgariff
• Caloric restriction in adult female mice alters metabolic regulation of reproductive systems - Hugo WG Herron-Vellacott
• Single-cell transcriptomic analysis reveals increased tumour cluster dominance and patient-specific divergence in gonadotroph adenoma recurrence - Yeung-Ae Park

• Expanding the CASR variant landscape: integrated in silico and structural triage of previously unreported germline variants - Sarah C Brennan
• Preserved renal function in severe hypercalcemia associated with Acquired Hypocalciuric Hypercalcemia (AHH) - Daiki Narita
• Long-term Management of Two Patients with Hypoparathyroidism Treated with Palopegteriparatide - Maho Taguchi
• A Translational Study of the Novel Dental Phenotype Associated with Familial Hypocalciuric Hypercalcemia - Jean-Philippe Bertocchio
• Hypercalcaemia and metastatic calcification following chronic calcium loading: a novel role for calcimimetic therapy - Patrice M Forner
•   From association to mechanism: rs838717 in regulation of DGKD and CaSR signalling in kidney stone disease - Catherine E Lovegrove

Title: Clinical Insights: Testosterone Therapy for Women & Men
Speaker: Dr Natassia Rodrigo

This presentation will explore the evidence-based use of testosterone therapy in women and men, focusing on appropriate patient selection, prescribing considerations, and ongoing monitoring.

The presentation will review AndroFeme® 1, the world’s first licensed testosterone cream developed specifically for women with hypoactive sexual desire disorder (HSDD), and AndroForte® 5, Australia’s only PBS-listed scrotal testosterone cream for male androgen deficiency.

Title: Meet the NEW Anabolic – Eladynos (abaloparatide)*: From Science to Patient Selection

Join Theramex for an interactive session on abaloparatide in the management of osteoporosis, led by A/Prof Kirtan Ganda, Professor Jacqueline Center and Dr Shoshana Sztal-Mazer.

The session opens with a welcome, introduction and learning objectives, and an introduction of A/Prof Kirtan Ganda by Theramex. A/Prof Ganda then presents the science behind abaloparatide. Three case studies follow: a first line PBS patient presented by Professor Jacqueline Center, a second line PBS patient presented by A/Prof Kirtan Ganda, and a private prescription patient presented by Dr Shoshana Sztal-Mazer. The session finishes with an interactive panel discussion and Q&A with all faculty, and a summary of the key take-home messages from A/Prof Ganda.

Synopsis
Most doctors use social media, but few have ever been taught how to navigate the professional and regulatory risks involved. A seemingly harmless social media post can attract complaints, regulatory scrutiny or lasting reputational damage.
This practical session examines where doctors most commonly get into trouble on social media, and how to avoid preventable mistakes.
This presentation will teach participants a practical framework for decision-making and content curation on social media. It will equip the audience to use social media confidently while protecting their professional reputation.

Speaker: Dr Maria Li
About the Speaker:
Dr Maria Li is a GP, social media science communicator, and social media strategy advisor. She regularly collaborates with health organisations, government agencies, and healthcare professionals across Australia to develop evidence-based social media content on a broad range of health topics.
Maria is Social Media Strategy Advisor to the Royal Australian College of General Practitioners, and a member of the World Health Organization’s Fides network of social media health influencers. She writes for the Medical Journal of Australia’s InSight+ on the topic of social media dos and don’ts for doctors.
Maria is the host and producer of The Safe Practice Podcast and co-host of The Good GP, Australia’s largest GP education podcast.

3:10PM - Panel Q&A 

• Thyroid and Pregnancy - Carolyn Allan
• The Peptide Problem: Therapeutic Folly, False Promise and Clinical Consequences  - Gary Wittert
• From Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome: Research and Clinical Implications - Anju Joham and Helena Teede

Co-Chair: Ghada el-Hajj Fuleihan

• CASRdb: A Comprehensive Database for Disease-associated Calcium-sensing Receptor Variants - Nipith Charoenngam
• Adaptive phenotypes for the human calcium-sensing receptor polymorphism R990G - Barbara Sinigaglia
• Identification and functional characterisation of calcium sensing receptor variants in patients presenting with calcium disorders: a thirty-year screening program - Bryan K Ward

• Engineering the human endometrium to investigate endometrial-associated disease and infertility - Harriet Fitzgerald
• IMAGING ACROSS SCALES – CATCHING CONCURRENT ORGANELLE DYNAMICS IN LIVING CELLS AND TISSUES - Senthil Arumugam
• Methods to Identify and Study Secreted Proteins in Cardiometabolic Disease - Brian Drew
• Mapping neuroendocrine organisation and plasticity with spatial transcriptomics - K Kamstra

• Long-Term Persistence with Denosumab and Bisphosphonates after Fracture and Its Association with Clinical Outcomes: A Population-Based Linked Cohort Study - Mike Lin
• Longitudinal changes in bone microarchitecture during gender-affirming hormone therapy: a 24-month prospective HR-pQCT study in transgender adults - Ingrid Bretherton
• Development of a National Multidisciplinary Consensus Statement on Medication-Related Osteonecrosis of the Jaw (MRONJ) and Osteoporosis in Australia - Christian Girgis
• Predictors of re-fracture and mortality within a secondary fracture prevention program: insights from up to 15-years follow-up     - Mawson Wang
• The effect of osteocalcin and GPRC6A silencing on insulin sensitivity in myotubes from older women - Itamar Levinger
• Hiding in plain sight: hypercalcaemia associated with calcium sulphate beads - Stefan Rietz
• Trabecular bone score independently predicts minimal trauma fracture vs more-than-minimal trauma fracture in an Australian re-fracture prevention clinic cohort   - Neha Chandrasekar
• Management of aromatase inhibitor-associated bone loss in women with hormone receptor-positive breast cancer: a single centre experience - Kimchi Do
• Rates of electrolyte derangements associated with ferric derisomaltose and denosumab co-administration amongst an adult inpatient cohort in a metropolitan Australia health service - Alec Ronan

• Assessing Diversity, Equity and Inclusion Across the Society for Reproductive Biology - Natalie Hannan
• Navigating academia: a journey of opportunity and challenges - Brendan Houston
• Bisphenols, fertility, and my path in research - Alexandra Peters

• Epigenetic profiling of human parathyroids: reduced activity of CaSR-specific enhancer in hyperparathyroidism** - Michael Mannstadt
• From CaSR-GABAB receptor heteromerization to amyloid-beta-driven tonic PTH hypersecretion in hyperparathyroidism - Chia-Ling Tu
• A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects - Carsten Alexander Wagner

Martyn Bullock’s abstract is the ‘Recipient of the ESA Paul Lee Best Abstract Award (Basic Science)’

Gary Wittert’s abstract is the ‘Recipient of the ESA Best Clinical Abstract Award’

• Thyroid dedifferentiation remodels the tumour ecosystem through cytokine-mediated immune reprogramming - Martyn Bullock
• Whole-Slide Deep Learning Prediction of BRAF^V600E Status in Papillary Thyroid Carcinoma - Ziba Gandomkar
• Targeting HTR2B to enhance β-cell proliferation in porcine islet xenotransplantation for  cure of type 1 diabetes  - Demi J Kaplan
• Comprehensive characterisation of androgen biosynthesis in the fat-tailed dunnart reveals developmental shifts in steroidogenic pathways - Ben M Lawrence
•  Effects of four years testosterone treatment on glycaemia, anthropometry, quality of life and safety: The T4DM RUN-ON sub-study. - Gary Wittert
• Tirzepatide and Resistance Exercise training (T±REx) for obesity therapy: a randomised controlled trial. - Bu B Yeap
• Scaled Testosterone: A Novel Metric to Calibrate Serum Testosterone and SHBG in Men - David J Handelsman
• Predicting circulating testosterone concentrations in individual men - Bu B Yeap

Co-Chair: Mike Collins

• CaSR Signalling, Mineral Metabolism, and Genetic Susceptibility to Kidney Stone Disease - Catherine Lovegrove
• CaSR phosphate sensing in murine parathyroid glands and cultured human thyroid parafollicular TT cells - Donald Ward
• The CaSR has only a PTH-dependent role in the acute response of renal phosphate transporters to phosphate intake. - Carsten Wagner
• Natural History, Diagnostic Pathway, and Treatment Patterns in Autosomal Dominant Hypocalcemia Type 1 (ADH1): Insights from the French Epi-Hypo Registry - Jean-Philippe Bertocchio

• Beyond ‘normal’ thyroid function tests: Resistance to thyroid hormone alpha (RTH) identified through reverse phenotyping - Sarah Goh
• A rare form of congenital adrenal hyperplasia due to partial POR deficiency presenting with amenorrhea and infertility - Daniel Yagoub
• Bone to be wild: acromegaly and polyostotic fibrous dysplasia in an adult male with mccune albright syndrome  - Ning NZ Zhang
• A Mosaic PHEX Variant in Hypophosphatemic Rickets: Distinguishing Postzygotic Mutation from Sex Chromosome Aneuploidy - Wu Tzen (Alex) Lim

• Paternal Immune Regulation of Sperm RNAs and Epigenetic Inheritance - Colin Conine

• How paternal diet remodels the epididymal sperm proteome and programs offspring phenotypes - David Skerrett-Byrne

Award sponsored by by: 

• A simple intervention to improve telehealth utilisation in General Endocrinology clinic - Cecilia LH Xu
• The Sustainable Endocrinology Clinic - Rita Upreti
• Patient characteristics and discharge pathways in a hospital-based specialist bone and mineral telehealth rapid access clinic service (Bone-TRACS) - Abraham Shamshad
• Balancing the Pursuit of Cure and Testing Burden in Primary Aldosteronism: A Patient Preference Study - Yafei Si